| ncRNA name | Keap1 siRNA |
| ncRNA Category | siRNA |
| Disease name | diabetic retinopathy (DR) |
| Species | Bos taurus |
| Tissues/Cell_line | bovine retinal endothelial cells (BRECs) |
| Methods | siRNA transfection, qPCR, CHIP assay, immunofluorescence |
| Expression pattern | associated |
| Functional description | Transfection of retinal endothelial cells with Keap1-siRNA prevented a glucose-induced decrease in Nrf2 accumulation in the nucleus, and this was accompanied by amelioration of decrease in GCLC expression. |
| PubMed ID | 23633659 |
| Year | 2013 |
| Title | Transcription factor Nrf2-mediated antioxidant defense system in the development of diabetic retinopathy. |
| Drug-related ncRNA | NO |
Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.